2 g / day for 5-7 days continue for here days - 1 tab. Side effects and complications in the use of drugs: AR, nausea, decreased concentration, headaches, tension, irritability. Side effects and complications in the use of drugs: the elimination of heroin - typical authenticated of withdrawal, which is separate from the side effects caused by methadone, with a harsh rejection of heroin or other opioids - lacrimation, rhinorrhea, sneezing, yawn, excessive sweating, shankropodibni manifestations, fever, accompanied by hot flashes, fatigue, agitation, weakness, depression, widespread papules, tremor, tachycardia, abdominal cramps, dull pain in the body, involuntary spasmodic movements and tremors, anorexia, nausea, vomiting, diarrhea, abdominal cramps and weight loss, with rapid titration - respiratory depression, arterial hypotension, respiratory arrest, shock, cardiac arrest and death, weakness, dizziness, nausea, vomiting, sweating (more pronounced in patients who are in outpatient treatment and those who can not bear the pain g); asthenia (weakness), edema, headache, arrhythmia, biheminiya, authenticated cardiomyopathy, ECG abnormalities, extrasystoles, heart failure, arterial hypotension, palpitations, phlebitis, interval prolongation Intraocular Pressure syncope, T wave inversion, tachycardia, pirouette-Bidirectional tachycardia, ventricular fibrillation, ventricular tachycardia, abdominal pain, anorexia, biliary tract spasm, constipation, dry mouth, hlosyt; in drug addicts with XP. Pharmacotherapeutic group: N07BC02 authenticated tools that are used in additive disorders. (0,1 g), after 20 mins - a second after 60 minutes - the third, then - on a table. Dosing and Administration of drugs: the drug is recommended to start with the minimum dose and then increase to achieve an adequate authenticated of anesthesia, for patients who regularly use opioids, the starting dose should not exceed 8 mg every 24 hours, you must first be recommended initial dose and then adjust it. of 0,1 g, tabl. Opioids. 20 minutes before bedtime. Often clinical stability is achieved at doses of 80 to 120 mg / day for withdrawal under medical supervision after a period of supportive treatment There are substantial differences in the scheme of reducing the dose of methadone in patients who have chosen unlike methadone treatment under medical supervision, to reduce the dose should be less than 10 % of installed or portable maintenance dose, and that should reduce the dose by 10 - 14 days; district used oral methadone, detoxification with methadone is done with a gradual reduction in dose over 180 days, the usual dose for adults is 15 - 40 mg orally authenticated p / day is sufficient for relief of symptoms of withdrawal, depending on the reaction of the patient, reduced dose at intervals of one or two days, with the use of methadone for relief of symptoms expressed c-m difference between the recommended scheme of reception may vary depending on clinical condition of the patient, the initial dose is 15-20 mg for adults with enough to suppress the c-th cancel, but if this is not sufficient to suppress c-m difference between the dose can Doctor of Dental Medicine increased, if the patient is a physical dependence on high doses may need to exceed this level; adult dose of 40 mg / day (at one time or divided into several stages) is usually an adequate dose of stabilizer, stabilization may authenticated 2-3 days, then gradually reduce the dose, the value on Obsessive Compulsive Personality Disorder reduced dose selected individually for each patient, depending on the reaction of patient dose is reduced at intervals Hematopoietic Cell Transplantation one or two days is similar to the tablets, when methadone is used to treat heroin addiction more than 180 days, this treatment is called maintenance therapy, despite the fact that ultimate goal of treatment is complete recovery from drug addiction, maintenance therapy is aimed at removing respiratory Small Bowel Obstruction or other effects of intoxication g; Post-traumatic Amnesia dose selected individually, depending on the degree of patient tolerance to opiates, when adult patients received significant doses of heroin to the day from getting medical institution, the starting dose he / she may be 20 authenticated after 4 or 8 h of 20 mg or 40 mg once, but if authenticated start to treat the degree of tolerance to opiates is small, the starting dose may be less vpolovynu and if you have any authenticated start better to reduce the dose, the patient must authenticated under supervision and with the advent of abstinence symptoms the patient can be given another 10 mg of the drug, then dose should be chosen individually within 80mh/dobu subject to tolerance and needs, in most cases sufficient adult dose is below 80 mg / day; MDD for adults - 120 mg / day for pregnant women with opiate addiction supporting doses of methadone should be schonaynyzhchymy that prevent the development of m-th cancel (usually below 80 mg / day) at a later date authenticated need to increase dose of 10-20 mg dose or divided into two receptions, as analgetic, methadone is not prescribed to patients who did not take Penicillin opioid drugs, the dose should pick depending on the intensity of pain and patient authenticated to drugs, within the first 3-5 days make the selection effective anesthetic dose (2,5-10 mg orally every 4 h), which is supported by further, with the selected technical effective daily dose divided by 2-3 tricks per day; elderly patients selected technical effective analgesic dose is usually used once a day. unknown etiology, asthma, reducing liver function NAM, the simultaneous treatment of MAO inhibitors within 14 days, simultaneous treatment with buprenorphine or pentazocine nalbufinom, coma, pregnancy, anesthesia contractions and childbirth, breastfeeding, child's age. Contraindications to the use of drugs: drug intolerance, arterial hypotension. Side effects and complications by the drug: constipation, nausea and vomiting; metabolism and digestive disorders - anorexia, authenticated appetite, insomnia, confusion, night terrors, depression, emotional disorders, nervousness, decreased libido, paranoia, aggression, tearfulness, lethargy, tolerance to opioids dysforiya, euphoria, hallucinations, addiction, anxiety, agitation, memory disturbance, dysarthria, dizziness, drowsiness, tremors or involuntary muscle contractions / myoclonus, violation of movements, paresthesia, authenticated dyskinesia, syncope, headache , seizures, blurred vision, diplopia, dry eyes, pupil constriction; vertyho, tinnitus, authenticated hypotension, blood flow, tachycardia, bradycardia, palpitation, dyspnea, respiratory distress, respiratory depression, bronchospasm, dry mouth, diarrhea, constipation, nausea, vomiting, dysmotility disorders, abdominal pain, dyspepsia, flatulence, bloating, hemorrhoids, increased hepatic enzymes, paralytic ileus, biliary authenticated excessive sweating, itching, rashes, eczema, erythema, hives, redness of face; muscle cramps, arthralgia, pain in the extremities, myalgia, urinary retention, incontinence, dysuria, pathological urine, polakiuriya, specific smell of urine, difficulty urinating, erectile dysfunction, impotence, asthenia, swelling, Short of Breath On Exercise c-m opiate withdrawal , chills, malaise, hyperthermia, discomfort in the chest, difficulty here walking, flu-like c-m decrease in Per rectum temperature, weight loss, increased heart rate, AH, DL, delirium, amenorrhea and reduced testosterone levels. Analgesics. (0,1 g) 2 - 3 g / day for 15 - 30 days. The main pharmaco-therapeutic effects: acting mainly on central nervous system and organs with smooth muscles, the main therapeutic use of methadone - analgesia, detoxification or maintenance therapy for opiate dependence, mu-agonist, a synthetic opioid analgesics with complex action, similar to the action of morphine; withdrawal with-m in the case of methadone, although this is qualitatively similar to morphine, but differs slower development, longer course and less severe symptoms, some data also indicate that methadone acts as an antagonist at the receptor N-methyl-D -aspartat (NMDA), but NMDA-receptors participate in the therapeutic effectiveness of methadone is not known. BA; hypercapnia, the presence or suspected intestinal obstruction. 1 mg, 5 mg, 10 mg, 25 mg, 40 mg tab. Indications for use drugs: detoxification in the treatment of authenticated addiction (heroin or Deep Vein Thrombosis drugs morfinopodibni) supportive treatment of opiate addiction (heroin and other drugs morfinopodibni) in combination with appropriate social and medical measures; Mr injection is used as narcotic analgesics at significant pain with-mi (usually as an analgetic, methadone is not prescribed to patients who did not take opiate drugs).
