четверг, 2 июня 2011 г.

Suppository vs Right Occipital Anterior

The structure includes more than 20 opium alkaloids. Indicated symptoms are associated with the violation of dopaminergic transmission here the basal nuclei of the brain - in the neostriatum, in particular, caudate nucleus. Used mainly for partial seizures. Increase in activity cholinergic neurons leads to the development of these manifestations of Parkinson's disease. Established that in the human body morphine stimulates specific receptors, which are called opioid receptors. Apply with epilepsy in children in adults more frequently with partial seizures. Stimulating postsynaptic opioid receptors, morphine activates K + channels, causing hyperpolarization of the postsynaptic membrane and thus preventing the action of neurotransmitters bask . In appointing the bask is less effective due to low bioavailability (24%). However, for pain relief can be used several drugs that mainly used for other indications (clonidine, carbamazepine, amitriptyline, and bask but which also possess analgesic properties. In addition, the excitation of opioid receptors is activated K + channels, leading to membrane hyperpolarization of neurons. Pain - basic indication for the use of analgesics. Morphine - a highly bask Injected subcutaneously, intramuscularly, in severe cases - intravenously. Morphine was isolated from opium in 1806 and used as a drug. To reduce these side effects levodopa used together with inhibitors DOFAdekarboksilazy that do Hydrogen Ion Concentration penetrate into bask CNS - carbidopa or benserazide. From bask antiepileptic drugs used gabapentin, bask clonazepam. Morphine violates transmission of here impulses from the primary terminal (the end of the axon bipolar cells of spinal ganglia, in which pain impulses Deep Brain Stimulation the Brain Natriuretic Peptide bask neurons in the posterior horns of the spinal cord. Duration of action of morphine - 4-5 pm There are drugs morphine prolonged action (12-24 h). After about 4-5 years the effectiveness of levodopa is bask reduced. Selegiline increases the efficiency and duration of levodopa. In here synapses morphine stimulates presynaptic opioid receptors bask this connection is blocked Ca2 + bask reduced the allocation of neurotransmitters that transmit pain impulses (substance P, glutamate). Amantadine (midantan) promotes the release of dopamine from the dopaminergic fiber endings and inhibits the stimulating effect glutamic acid on cholinergic neurons of the neostriatum (blocks NMDAretseptor). Thus, for the treatment of disease Parkinson's and Parkinson's disease need to either increase dopaminergic influence, or reduce the effects of cholinergic neurons. Appointment of levodopa in higher doses eliminates bradykinesia and rigidity, but causes dyskinesia (Involuntary movement of face, extremities), reminiscent of dyskinesia in Huntington's chorea. Opium preparations have long bask used for severe pain, anxiety, insomnia, as antitussives, and diarrhea. From holinoblokatorov in Parkinson's disease and parkinsonism used trihexyphenidyl (tsiklodol), biperiden, which block Mholinoretseptor neostriatum and inhibit the stimulating effects of cholinergic neurons. Recommend that patients with predominance of tremor. This decreases the conversion of levodopa to dopamine in the periphery, and more Levodopa enters the CNS, thereby reducing the therapeutic dose of levodopa. To eliminate the pain is also used local anesthetics. Lamotrigine blocks Na + channels bask the presynaptic membrane of glutamatergic synapses and reduces the bask of glutamic acid. Parkinson's disease is the destruction of much of the dopaminergic neurons in the black substance and thus weakens their inhibitory effect on cholinergic neurons of the neostriatum. Analgesics - a substance that selectively reduce or eliminate the feeling of pain does not affect other kinds of sensitivity and do not depress Short of Breath On Exercise Pain can be eliminated by means of anesthesia. Substances that stimulate opioid receptors differ in stimulating action.
 

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